Anti-PHLPP1 antibody

Catalog Number:

A001019537STJ

Mfr. No.:

STJ111739

Price:

$297

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Overview
- This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1508-1717 of human PHLPP1 (NP_919431. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Ph Domain Leucine-Rich Repeat-Containing Protein Phosphatase 1; Pleckstrin Homology Domain-Containing Family E Member 1; Ph Domain-Containing Family E Member 1; Suprachiasmatic Nucleus Circadian Oscillatory Protein; Hscop (Gene ID:23239; UniProt:O60346)
  
  * For research use only