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Overview
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Peroxiredoxin 1 is a protein encoded by the PRDX1 gene which is approximately 22, 1 kDa. Peroxiredoxin 1 is localised to the cytoplasm and melanosome. It is involved in gene expression, glucose and energy metabolism and cellular senescence. This protein falls under the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. It may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8+ T-cells. It may also play a role in cancer development or progression. Peroxiredoxin 1 is expressed in the nervous system, liver, lung, skin and pancreas. Mutations in the PRDX1 gene may result in anthrax disease. STJ97014 was developed from clone 8E7 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody detects endogenous Peroxiredoxin 1 protein.
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Overview
IF analysis of Hela with antibody (Left) and DAPI (Right) diluted at 1:100.
Western blot analysis of 1) MCF7, 2) Rat Kidney Tissue, 3) Mouse Brain Tissue, diluted at 1:2000.
Immunofluorescence analysis of Human-appendix tissue. 1, Peroxiredoxin 1 monoclonal antibody (8E7) (red) was diluted at 1:200 (4°C, overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).3, Picture B: DAPI (blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B Immunofluorescence analysis of Rat-brain tissue. 1, Peroxiredoxin 1 monoclonal antibody (8E7) (red) was diluted at 1:200 (4°C, overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).3, Picture B: DAPI (blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B Immunohistochemical analysis of paraffin-embedded Human-uterus-cancer tissue. 1, Peroxiredoxin 1 monoclonal antibody (8E7) was diluted at 1:200 (4°C, overnight). 2, Sodium citrate pH 6.0 was used for antibody retrieval (>98°C, 20min). 3, Secondary antibody was diluted at 1:200 (room tempeRature, 30min). Negative control was used by secondary antibody only.
Anti-Peroxiredoxin 1 antibody
Anti-Peroxiredoxin 1 antibody
Catalog Number:
A001052383STJ
Mfr. No.:
STJ97014
Price:
$224
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