Anti-PDK2 antibody

Catalog Number:

A001024650STJ

Mfr. No.:

STJ117807

Price:

$297

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Overview
- This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 128-407 of human PDK2 (NP_002602. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Pyruvate Dehydrogenase; Acetyl-Transferring Kinase Isozyme 2-Mitochondrial; Pyruvate Dehydrogenase Kinase Isoform 2; Pdh Kinase 2; PdkII (Gene ID:5164; UniProt:Q15119)
  
  * For research use only