Anti-PCBD1 antibody

Catalog Number:

A001036571STJ

Mfr. No.:

STJ28475

Price:

$297

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Overview
- This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-104 of human PCBD1 (NP_000272. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Pterin-4-Alpha-Carbinolamine Dehydratase; Phs; 4-Alpha-Hydroxy-Tetrahydropterin Dehydratase; Dimerization Cofactor Of Hepatocyte Nuclear Factor 1-Alpha; Dcoh; Dimerization Cofactor Of Hnf1; Phenylalanine Hydroxylase-Stimulating Protein; Pterin Carbinolamine Dehydratase; Pcd (Gene ID:5092; UniProt:P61457)
  
  * For research use only