Anti-PARL antibody

Catalog Number:

A001017317STJ

Mfr. No.:

STJ110531

Price:

$297

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Overview
- This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human PARL (NP_001032728. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Presenilins-Associated Rhomboid-Like Protein-Mitochondrial; Mitochondrial Intramembrane Cleaving Protease Parl Cleaved Into-P-Beta; Pbeta (Gene ID:55486; UniProt:Q9H300)
  
  * For research use only