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Overview
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The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
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Overview
Immunohistochemistry of paraffin-embedded mouse kidney using PAK2 antibody (STJ29472) at dilution of 1:100 (40x lens).
Immunofluorescence analysis of A549 cells using PAK2 antibody (STJ29472). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using PAK2 antibody (STJ29472) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-PAK2 antibody
Anti-PAK2 antibody
Catalog Number:
A001037453STJ
Mfr. No.:
STJ29472
Price:
$297
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