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Overview
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The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.
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Overview
Immunofluorescence analysis of mouse brain using P2RY12 antibody (STJ117783) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of C6 cells using P2RY12 antibody (STJ117783) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U-87MG cells using P2RY12 antibody (STJ117783) at dilution of 1:100. Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using P2RY12 antibody (STJ117783) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 180s.
Anti-P2RY12 antibody
Anti-P2RY12 antibody
Catalog Number:
A001024626STJ
Mfr. No.:
STJ117783
Price:
$297
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