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Overview
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This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
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- Properties
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Overview
Immunohistochemistry of paraffin-embedded human liver damage using OTC antibody (STJ111876) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using OTC antibody (STJ111876) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human prostate using OTC antibody (STJ111876) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using OTC antibody (STJ111876) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 1s.
Anti-OTC antibody
Anti-OTC antibody
Catalog Number:
A001019650STJ
Mfr. No.:
STJ111876
Price:
$297
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