Anti-Orexin R-1 antibody

Anti-Orexin R-1 antibody

Catalog Number:
A001050207STJ
Mfr. No.:
STJ94837
Price:
$224
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      • Overview
        • Orexin R-1 is a protein encoded by the HCRTR1 gene which is approximately 47, 5 kDa. Orexin R-1 is localised to the cell membrane. It is involved in peptide ligand-binding receptors, signalling by GPCR and RET signalling. It is a G-protein coupled receptor which acts as a moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Orexin R-1 is expressed in the nervous system. Mutations in the HCRTR1 gene may result in rapid-onset obesity with hypothalamic dysfunction and narcolepsy. STJ94837 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of orexin R-1 protein.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Synthesized peptide derived from human Orexin R-1
          Purification
          The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
          Conjugate
          Unconjugated
          Formulation
          Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
          Storage
          Store at -20°C and avoid repeat freeze-thaw cycles.
          Concentration
          1 mg/ml
          Regulatory Status
          RUO
          Antigen
          Orexin Receptor Type 1; Ox-1-R; Ox1-R; Ox1r; Hypocretin Receptor Type 1 (Gene ID:3061; UniProt:O43613)

          * For research use only

      • Applications
        • Application
          IF; ELISA
        • Application Dilutions
          IF 1:200-1:1000
          ELISA 1:20000

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