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Overview
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OTUB2 is a protein encoded by the OTUB2 gene which is approximately 27, 2 kDa. OTUB2 is localised to the nucleus. It is involved in the metabolism of proteins, deubiquitination and ovarian tumor domain proteases. OTUB2 is one of several deubiquitylating enzymes. It is a hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Ubiquitin modification of proteins is needed for their stability and function. OTUB2 is widely expressed with higher expression in the brain. STJ94840 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of OTUB2 protein.
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Overview