Anti-OLR1 antibody

Catalog Number:

A001034603STJ

Mfr. No.:

STJ24865

Price:

$297

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Overview
- This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 58-273 of human OLR1 (NP_002534. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Oxidized Low-Density Lipoprotein Receptor 1; Ox-Ldl Receptor 1; C-Type Lectin Domain Family 8 Member A; Lectin-Like Oxidized Ldl Receptor 1; Lox-1; Lectin-Like Oxldl Receptor 1; Hlox-1; Lectin-Type Oxidized Ldl Receptor 1 Cleaved Into-Oxidized Low-Density Lipoprotein Receptor 1-Soluble Form (Gene ID:4973; UniProt:P78380)
  
  * For research use only