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Overview
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This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.
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Overview
Immunoprecipitation analysis of 200ug extracts of MCF-7 cells, using 3 ug OAT antibody (STJ27991). Western blot was performed from the immunoprecipitate using OAT antibody (STJ27991) at a dilition of 1:1000.
Western blot analysis of extracts of various cell lines, using OAT antibody (STJ27991) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 10s.
Anti-OAT antibody
Anti-OAT antibody
Catalog Number:
A001036240STJ
Mfr. No.:
STJ27991
Price:
$297
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