Name: Anti-Nucleoprotein of Puumula Virus (PUUV). IgG fraction monoclonal antibody. Clone 1G3/H10
Price: 878.00 USD

- Overview
  - Mouse monoclonal antibody IgG fraction (clone 1G3/H10) obtained by immunizing mice with purified recombinant PUUV Nucleoprotein. The IgG fraction was purified using Protein G-Sepharose.
    
    Please contact us at for specific academic pricing.
- Properties
  - Antibody Type
    
    monoclonal
    
    Isotype
    
    IgG1
    
    Formulation
    
    Solution at 1.0 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial.
    
    Storage
    
    Store at -20°C.
    
    * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.
- Applications
  - Application Description
    
    This antibody can be used in ELISA (1:50,000 dilution) and Western blot (1:20,000 dilution) analysis. It recognizes specifically the nucleoprotein of PUUV. Hantaviruses (family Bunyaviridae) are enveloped viruses that contain a tripartite, negative-stranded RNA genome encoding an RNA-dependent RNA polymerase (L), two integral membrane glycoproteins (G1 and G2), and a nucleocapsid (N) protein. The N protein is the most abundant viral component and the major antigen in early serological response in humans and mice. It has essential functions in viral RNA replication, encapsidation, and also in virus assembly. PUUV is a causative agent of a mild form of hemorrhagic fever with renal syndrome (nephropathia epidemica) mainly in Europe and it is transmitted by the red bank vole Clethrionomys glareolus.
- Reference
  - Lindgren, L. et al. (2006) Virus Genes 33, 169-174.
    Plyusnin, A. et al (2001) Adv. Virus Res. 57, 105-136.
    Sironen, T. et al. (2001) J. Virol. 75, 11803-11810.
    Stohwasser, R. et al. (1990) Virology 174, 79-86.

Anti-Nucleoprotein of Puumula Virus (PUUV). IgG fraction monoclonal antibody. Clone 1G3/H10

Anti-Nucleoprotein of Puumula Virus (PUUV). IgG fraction monoclonal antibody. Clone 1G3/H10

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