Name: Anti-Nucleoprotein of Dobrava Virus (DOBV). IgG fraction monoclonal antibody. Clone 3A1/H9
Price: 878.00 USD

- Overview
  - Mouse monoclonal antibody IgG fraction (clone 3A1/H9) obtained by immunizing mice with purified recombinant DOBV Nucleoprotein. The IgG fraction was purified using Protein G-Sepharose.
    
    Please contact us at for specific academic pricing.
- Properties
  - Antibody Type
    
    monoclonal
    
    Isotype
    
    IgG1
    
    Formulation
    
    Solution at 1.0 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial.
    
    Storage
    
    Store at -20°C.
    
    * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.
- Applications
  - Application Description
    
    This antibody can be used in ELISA (1:30,000 dilution) and Western blot (1:15,000 dilution) analysis. It recognizes the nucleoprotein of DOBV and it has cross reactivity with nucleoproteins of Seoul Virus (SEOV) and Hantaan Virus (HTNV). Hantaviruses (family Bunyaviridae) are enveloped viruses that contain a tripartite, negative-stranded RNA genome encoding an RNA-dependent RNA polymerase (L), two integral membrane glycoproteins (G1 and G2), and a nucleocapsid (N) protein. The N protein is the most abundant viral component and the major antigen in early serological response in humans and mice. It has essential functions in viral RNA replication, encapsidation, and also in virus assembly. DOBV causes hemorrhagic fever with renal syndrome in central Europe and is carried by two different rodent species, Apodemus flavicollis and Apodemus agrarius.
- Reference
  - Klempa, B. et al. (2004) J. Clin. Microbiol. 42, 1322-1325.
    Vapalahti, O. et al (2003) Lancet Infect. Dis. 3, 653-661.
    Sibold, C. et al (2001) J. Med. Virol. 63, 158-167.
    Avsic-Zupanc, T. et al. (1995) J. Gen. Virol. 76, 2801-2808.

Anti-Nucleoprotein of Dobrava Virus (DOBV). IgG fraction monoclonal antibody. Clone 3A1/H9

Anti-Nucleoprotein of Dobrava Virus (DOBV). IgG fraction monoclonal antibody. Clone 3A1/H9

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