Anti-NOVA1 antibody

Catalog Number:

A001020977STJ

Mfr. No.:

STJ113931

Price:

$297

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Overview
- This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 408-507 of human NOVA1 (NP_002506. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Rna-Binding Protein Nova-1; Neuro-Oncological Ventral Antigen 1; Onconeural Ventral Antigen 1; Paraneoplastic Ri Antigen; Ventral Neuron-Specific Protein 1 (Gene ID:4857; UniProt:P51513)
  
  * For research use only