Name: Anti-NOS2 antibody
Price: 224.00 USD

Overview
- NOS2 is a protein encoded by the NOS2 gene which is approximately 131, 1 kDa. NOS2 is localised to the cytoplasm. It is involved in arginine biosynthesis, toxoplasmosis, G-beta gamma signalling and PEDF induced signalling. It is a nitric oxide synthase messenger molecule with diverse functions throughout the body. In macrophages, it mediates tumoricidal and bactericidal actions and is also involved in inflammation by enhancing the synthesis of proinflammatory mediators such as IL6 and IL8. NOS2 is expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Mutations in the NOS2 gene may result in borderline leprosy and Peyronies disease. STJ94534 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of NOS2 protein.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Synthesized peptide derived from human NOS2 around the non-phosphorylation site of Y151.
  
  Purification
  
  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Concentration
  
  1 mg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Nitric Oxide Synthase-Inducible; Hepatocyte Nos; Hep-Nos; Inducible No Synthase; Inducible Nos; Inos; Nos Type II; Peptidyl-Cysteine S-Nitrosylase Nos2 (Gene ID:4843; UniProt:P35228)
  
  * For research use only