Anti-NDC80 antibody

Catalog Number:

A001035832STJ

Mfr. No.:

STJ27364

Price:

$297

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Overview
- This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 343-642 of human NDC80 (NP_006092. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Kinetochore Protein Ndc80 Homolog; Highly Expressed In Cancer Protein; Kinetochore Protein Hec1; Hshec1; Kinetochore-Associated Protein 2; Retinoblastoma-Associated Protein Hec (Gene ID:10403; UniProt:O14777)
  
  * For research use only