Anti-NCOR2 antibody

Catalog Number:

A001017440STJ

Mfr. No.:

STJ110686

Price:

$297

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Overview
- This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone-and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 670-900 of human NCOR2 (NP_006303. 4).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Nuclear Receptor Corepressor 2; N-Cor2; Ctg Repeat Protein 26; Smap270; Silencing Mediator Of Retinoic Acid And Thyroid Hormone Receptor; Smrt; T3 Receptor-Associating Factor; Trac; Thyroid--Retinoic-Acid-Receptor-Associated Corepressor (Gene ID:9612; UniProt:Q9Y618)
  
  * For research use only