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Overview
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Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.
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- Properties
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Overview
Immunofluorescence analysis of rat skeletal muscle using MYH7 antibody (STJ29702) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded mouse heart using MYH7 antibody (STJ29702) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of Mouse heart, using MYH7 Rabbit pAb (STJ29702) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 180s.
Immunohistochemistry of paraffin-embedded mouse skeletal muscle using MYH7 antibody (STJ29702) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of Rat heart, using MYH7 Rabbit pAb (STJ29702) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-MYH7 antibody
Anti-MYH7 antibody
Catalog Number:
A001037658STJ
Mfr. No.:
STJ29702
Price:
$297
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