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Overview
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This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Overview
Immunohistochemistry of paraffin-embedded mouse brain using MYCN antibody (STJ24658) (40x lens).
Immunohistochemistry of paraffin-embedded rat brain using MYCN antibody (STJ24658) (40x lens).
Western blot analysis of extracts of various cell lines, using MYCN antibody (STJ24658) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 90s.
Anti-MYCN antibody
Anti-MYCN antibody
Catalog Number:
A001034486STJ
Mfr. No.:
STJ24658
Price:
$297
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