Name: Anti-Mouse CD11b In Vivo Antibody - Low Endotoxin (M1/70)
Price: 680.00 USD

- Overview
  - Antigen Distribution: The Mac-1 CD11b antigen is present on macrophages, granulocytes, natural killer cells, blood monocytes. CD11b is expressed on 8% spleen cells, 44% bone marrow cells and less than 1% of thymocytes.
    Specificity: Anti-CD11b In Vivo Antibody - Low Endotoxin (M1/70) recognizes the (Mr 170 kD) alpha m subunit of Mac-1 (CD11b/CD18, alpha m beta 2 integrin), the mouse macrophage-granulocyte specific antigen. Mac-1 is a macrophage differentiation antigen associated with type three complement receptor and mediates adhesion to CD54 (ICAM-1).
    Isotype Control: Rat IgG2b In Vivo Isotype Control - Low Endotoxin [1-2] (ICH2243)
    Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
    Aggregation: Aggregation level ≤ 5%
    
    Please contact us at for specific academic pricing.
- Properties
  - Host
    
    rat
    
    Isotype
    
    IgG2b
    
    Reactivity
    
    mouse
    
    Clone
    
    M1/70
    
    Immunogen
    
    B10 mouse spleen cells enriched for T cells
    
    Purification
    
    >95% by SDS-PAGE and HPLC
    
    Formulation
    
    0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
    
    Storage
    
    anti-CD11b In Vivo Antibody - Low Endotoxin (M1/70) is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
    
    Molecular Weight
    
    0.5 mg/ml
    
    Regulatory Status
    
    Functional Assay: Activation of mouse peritoneal macrophages
    Each investigator should determine their own optimal working dilution for specific applications.
    
    Antigen
    
    (Gene ID:Integrin alpha-M, Itgam, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1)
    
    * Products are for research use only. Not for use in diagnostic or therapeutic procedures.
- Applications
  - Application
    
    Immunoprecipitation; WB; Functional Assays; Flow Cytometry; IHC (frozen); CyTOF; Immunocytochemistry

Anti-Mouse CD11b In Vivo Antibody - Low Endotoxin (M1/70)

Anti-Mouse CD11b In Vivo Antibody - Low Endotoxin (M1/70)

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