Anti-MATK antibody

Anti-MATK antibody

Catalog Number:
A001036807STJ
Mfr. No.:
STJ28734
Price:
$297
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      • Overview
        • The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 352-466 of human MATK (NP_647611. 1).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Megakaryocyte-Associated Tyrosine-Protein Kinase; Csk Homologous Kinase; Chk; Hematopoietic Consensus Tyrosine-Lacking Kinase; Protein Kinase Hyl; Tyrosine-Protein Kinase Ctk (Gene ID:4145; UniProt:P42679)

          * For research use only

      • Applications
        • Application
          WB; IHC
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:50-1:200

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