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Overview
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This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.
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Overview
Immunofluorescence analysis of U2OS cells using LMNB2 antibody (STJ28566). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded mouse brain using LMNB2 Antibody (STJ28566) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat brain using LMNB2 Antibody (STJ28566) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human adenomyosis using LMNB2 Antibody (STJ28566) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using LMNB2 antibody (STJ28566) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 90s.
Anti-LMNB2 antibody
Anti-LMNB2 antibody
Catalog Number:
A001036658STJ
Mfr. No.:
STJ28566
Price:
$297
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