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Overview
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In both males and females, LH is essential for reproduction. In females FSH initiates follicular growth and at the time of the maturation of the follicle the estrogen rise leads to a release of LH over a 24–48 hour period. This 'LH surge' triggers ovulation thereby not only releasing the egg, but also initiating the conversion of the residual follicle into a corpus luteum that, in turn, produces progesterone to prepare the endometrium for a possible implantation. LH is necessary to maintain luteal function for the first two weeks. In case of a pregnancy luteal function will be further maintained by the action of hCG from the newly established pregnancy. In the male, LH acts upon the Leydig cells of the testis and is responsible for the production of testosterone.
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Overview