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Overview
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Lactoferrin is a protein encoded by the LTF gene which is approximately 78, 1 kDa. Lactoferrin is localised to the cytoplasm and nucleus. It is involved in the innate immune system and the HIV life cycle. This protein falls under the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. It is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. Lactoferrin is expressed in the blood, bone marrow, lung, eye and liver. Mutations in the LTF gene may result in dry eye syndrome. STJ97062 was developed from clone Q100 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody detects endogenous Lactoferrin protein.
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Overview