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Overview
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The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.
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- Properties
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Overview
Immunofluorescence analysis of A549 cells using KPNA1 antibody (STJ24340).
Immunohistochemistry of paraffin-embedded human lung cancer using KPNA1 antibody (STJ24340) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human esophagus using KPNA1 antibody (STJ24340) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using KPNA1 antibody (STJ24340) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
Anti-KPNA1 antibody
Anti-KPNA1 antibody
Catalog Number:
A001034309STJ
Mfr. No.:
STJ24340
Price:
$297
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