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Overview
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This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine-and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with autosomal dominant mental retardation-32. Alternative splicing results in multiple transcript variants.
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- Properties
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Overview
Immunofluorescence analysis of NIH/3T3 cells using KAT6A antibody (STJ117202) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U2OS cells using KAT6A antibody (STJ117202) at dilution of 1:100. Blue: DAPI for nuclear staining.
Western blot analysis of extracts of 293T cells, using KAT6A antibody (STJ117202) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 10s.
Anti-KAT6A antibody
Anti-KAT6A antibody
Catalog Number:
A001024049STJ
Mfr. No.:
STJ117202
Price:
$297
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