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Overview
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The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
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- Properties
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Overview
Immunofluorescence analysis of Raw264.7 cells using JAK3 Polyclonal Antibody (STJ111020) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of THP-1 cells using JAK3 Polyclonal Antibody (STJ111020) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of U-87MG cells, using JAK3 antibody (STJ111020) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 90s.
Anti-JAK3 antibody
Anti-JAK3 antibody
Catalog Number:
A001018911STJ
Mfr. No.:
STJ111020
Price:
$297
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