Anti-ITGAE antibody

Anti-ITGAE antibody

Catalog Number:
A001019741STJ
Mfr. No.:
STJ111975
Price:
$297
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      • Overview
        • Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 19-200 of human ITGAE (NP_002199. 3).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Integrin Alpha-E; Hml-1 Antigen; Integrin Alpha-Iel; Mucosal Lymphocyte 1 Antigen; Cd Antigen Cd103 Cleaved Into-Integrin Alpha-E Light Chain-Integrin Alpha-E Heavy Chain (Gene ID:3682; UniProt:P38570)

          * For research use only

      • Applications
        • Application
          WB; IHC
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:50-1:200

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