-
-
Overview
-
This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.
Please contact us at for specific academic pricing.
-
- Properties
- Applications
-
Overview
Western blot analysis of extracts of various cell lines, using ISCU Antibody (STJ29162) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 10s.
Anti-ISCU antibody
Anti-ISCU antibody
Catalog Number:
A001037187STJ
Mfr. No.:
STJ29162
Price:
$297
Size:
Quantity:
Add to Cart:
.