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Overview
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This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment.
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Overview
Immunofluorescence analysis of HeLa cells using IRF5 antibody (STJ24230). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using IRF5 antibody (STJ24230) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 90s.
Anti-IRF5 antibody
Anti-IRF5 antibody
Catalog Number:
A001034256STJ
Mfr. No.:
STJ24230
Price:
$297
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