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Overview
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This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.
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Overview
Immunofluorescence analysis of C6 cells using IQGAP1 Polyclonal Antibody (STJ117817) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded mouse lung using IQGAP1 antibody (STJ117817) at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded human placenta using IQGAP1 antibody (STJ117817) at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded rat spleen using IQGAP1 antibody (STJ117817) at dilution of 1:200 (40x lens).
Western blot analysis of extracts of various cell lines, using IQGAP1 antibody (STJ117817) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 10s.
Anti-IQGAP1 antibody
Anti-IQGAP1 antibody
Catalog Number:
A001024660STJ
Mfr. No.:
STJ117817
Price:
$297
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