Anti-Infectious Pancreatic Necrosis Virus (IPNV) VP3 protein. IgG fraction monoclonal antibody (clone 6E1/F2)

Anti-Infectious Pancreatic Necrosis Virus (IPNV) VP3 protein. IgG fraction monoclonal antibody (clone 6E1/F2)

Catalog Number:
A001277592AUS
Mfr. No.:
AUST_FM-130DZ-5
Price:
$760
  • Size:
    100µg
    Quantity:
    Add to Cart:
      • Overview
        • Mouse monoclonal antibody IgG fraction (clone 6E1/F2) obtained by immunizing mice with purified IPN virus. The IgG fraction was purified using Protein G-Sepharose.

          Please contact us at for specific academic pricing.

      • Properties
        • Antibody Type
          monoclonal
          Formulation
          Solution at 0.5 mg/mL in PBS.
          Storage
          Store at -20°C.

          * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

      • Applications
        • Application Description
          This antibody can be used in ELISA (1:5,000 dilution), Western blot (1:1,000 dilution), and indirect immunofluorescence (1:500). It recognizes a 31 kDa protein corresponding to the structural VP3 protein. IPNV is a single-shelled, non-enveloped virus that belongs to the family Birnaviridae. Its genoma comprises a bisegmented double-stranded RNA, the segment B encodes VP1 and the segment A yields a polyprotein, pVP2-VP4-VP3 and a small protein (VP5) dispensable for viral replication. The polyprotein is autocatalytically cleaved by the endoprotease VP4 to release the structural proteins VP3 and pVP2. VP3 is an internal protein that interacts with both VP1 and dsRNA in a mutually independent mannner. IPNV is responsible for infectious pancreatic necrosis, a contagious fish disease characterized by severe damage to the internal organs and tissues with a high mortality among salmonids.
      • Reference
        • Pedersen, T. et al. (2007) J. Virol. 81, 6652-6663.
          Roberts, R. J. & Pearson MD. (2005) J. Fish Dis. 28, 383-390.
          Rodriguez Saint-Jean S. et al. (2003) 62, 113-165.
          Duncan, R. et al. (1991) Virology 181, 541-552.

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