Name: Anti-Infectious Pancreatic Necrosis Virus (IPNV). IgG fraction monoclonal antibody (clone 2F9/F1)
Price: 760.00 USD

- Overview
  - Mouse monoclonal antibody IgG fraction (clone 2F9/F1) obtained by immunizing mice with purified IPN virus. The IgG fraction was purified using Protein G-Sepharose.
    
    Please contact us at for specific academic pricing.
- Properties
  - Antibody Type
    
    monoclonal
    
    Formulation
    
    Solution at 1.0 mg/mL in PBS.
    
    Storage
    
    Store at -20°C.
    
    * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.
- Applications
  - Application Description
    
    This antibody is able to neutralize IPN virus and can be used in ELISA (1:5,000 dilution), Western blot (1:1,000 dilution), and indirect immunofluorescence (1:500). IPNV is a single-shelled, non-enveloped virus that belongs to the family Birnaviridae. Its genoma comprises a bisegmented double-stranded RNA, the segment B encodes VP1 and the segment A yields a polyprotein, pVP2-VP4-VP3 and a small protein (VP5) dispensable for viral replication. The polyprotein is autocatalytically cleaved by the endoprotease VP4 to release the structural proteins pVP2 (62 kDa) and VP3. pVP2 is processed during virus maturation into VP2 (54 kDa) constituting the outer capsid component. IPNV is responsible for infectious pancreatic necrosis, a contagious fish disease characterized by severe damage to the internal organs and tissues with a high mortality among salmonids.
- Reference
  - Roberts, R. J. & Pearson MD. (2005) J. Fish Dis. 28, 383-390.
    Galloux, M. et al. (2004) J. Gen. Virol. 85, 2231-2236.
    Rodriguez Saint-Jean S. et al. (2003) 62, 113-165.
    Duncan, R. et al. (1991) Virology 181, 541-552.

Anti-Infectious Pancreatic Necrosis Virus (IPNV). IgG fraction monoclonal antibody (clone 2F9/F1)

Anti-Infectious Pancreatic Necrosis Virus (IPNV). IgG fraction monoclonal antibody (clone 2F9/F1)

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