Anti-IL18R1 antibody

Catalog Number:

A001034225STJ

Mfr. No.:

STJ24172

Price:

$297

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Overview
- The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 19-320 of human IL18R1 (NP_003846. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Interleukin-18 Receptor 1; Il-18r-1; Il-18r1; Cd218 Antigen-Like Family Member A; Cdw218a; Il1 Receptor-Related Protein; Il-1rrp; Il1r-Rp; Interleukin-18 Receptor Alpha; Il-18r-Alpha; Il-18ralpha; Cd Antigen Cd218a (Gene ID:8809; UniProt:Q13478)
  
  * For research use only