Anti-IL17RB antibody

Catalog Number:

A001019948STJ

Mfr. No.:

STJ112186

Price:

$297

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Overview
- The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 18-292 of human IL17RB (NP_061195. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Interleukin-17 Receptor B; Il-17 Receptor B; Il-17rb; Cytokine Receptor-Like 4; Il-17 Receptor Homolog 1; Il-17rh1; Il17rh1; Interleukin-17b Receptor; Il-17b Receptor (Gene ID:55540; UniProt:Q9NRM6)
  
  * For research use only