Name: Anti-IFN-Alpha-antibody
Price: 451.00 USD

- Overview
  - The alpha interferons are involved in virus resistance in target cells for these viruses. They are knownto block cell proliferation and to regulate MHC class I antigen expression. The IFN alpha family has over 20genes and pseudogenes in two families (I and II), one with a mature length of 166aa and one of 172aa.Cells producing IFN alpha are lymphocytes, monocytes, macrophages and cell lines such as Namalwa andKGI. Bioassays for IFN alpha include cytopathic effect blocking, by viruses such as VSV, SFV and BMCV, ontheir target cells. A number of receptors for IFN alpha are now known and seem to be expressed on mostcell types. N27 is specific for human IFN alpha 2 and does not cross react with human IFN alpha 1.Immunogen: N27 reacts with linear peptide 43aa-53aa, placing the epitope outside theimmunodominant regions I and II.
    
    Please contact us at for specific academic pricing.
- Properties
  - Host
    
    mouse
    
    Antibody Type
    
    monoclonal
    
    Isotype
    
    IgG1 kappa
    
    Reactivity
    
    human
    
    Clone
    
    N27
    
    Immunogen
    
    E.coli derived recombinant human IFN?2c
    
    Conjugate
    
    Unconjugated
    
    Formulation
    
    100 µg affinity purified antibody, presented in PBS with 0, 02 % sodiumazide.
    
    Storage
    
    Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
    
    Regulatory Status
    
    RUO
    
    * For research use only
- Applications
  - Application
    
    IHC (frozen); WB; ELISA
    
    Application Description
    
    ELISA, WB (1-2 μg/ml), IHC frozen sections (1-2 μg/mlfor 30 min at RT)