Anti-human Vascular Endothelial Growth Factor receptor 1 (VEGFR-1 or FLT-1) IgG fraction (monoclonal)

Anti-human Vascular Endothelial Growth Factor receptor 1 (VEGFR-1 or FLT-1) IgG fraction (monoclonal)

Catalog Number:
A001277490AUS
Mfr. No.:
AUST_MR-851-4; AUST_MR-851-7
Price:
$520
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      • Overview
        • IgG fraction from mouse monoclonal antibody (clone 6D1/G11) obtained by immunization of mice with the extracellular domain of human VEGFR-1 (106 kDa). The IgG fraction was purified using Protein G-Sepharose.

          Please contact us at for specific academic pricing.

      • Properties
        • Antibody Type
          monoclonal
          Isotype
          IgG1
          Formulation
          Solution at 1.0 mg/mL in PBS
          Storage
          Store at -20°C.

          * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

      • Applications
        • Application Description
          This antibody can be used in ELISA assays (1: 8,000 dilution). It recognizes the extracellular domain of human VEGFR-1, a type I membrane protein. This protein binds VEGF, PLGF and VEGFB and belongs to the tyrosine protein kinase family. The VEGFR-1 has a signaling role in mediating monocyte chemotaxis in tumor disease and performs an inhibitory role by sequestering VEGF and preventing its interaction with VEGFR-2
      • Reference
        • Ferrara, N. et. al. (2003) Nat. Med. 9, 669 - 676; Cross, M.J. et. al. (2003) Trends Biochem. Sci. 28, 488 - 494.

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