Anti-human T-Cell Surface Glycoprotein CD8. IgG fraction (Monoclonal)

Anti-human T-Cell Surface Glycoprotein CD8. IgG fraction (Monoclonal)

Catalog Number:
A001277438AUS
Mfr. No.:
AUST_MA-CD8-6
Price:
$520
  • Size:
    200µg
    Quantity:
    Add to Cart:
      • Overview
        • IgG fraction from mouse monoclonal antibody (clone 1C8/D8) obtained by immunization of mice with human CD8+ T- lymphocyte. The IgG fraction was purified using Protein G-Sepharose.

          Please contact us at for specific academic pricing.

      • Properties
        • Antibody Type
          monoclonal
          Isotype
          IgG2a
          Formulation
          Solution at 0.5 mg/mL in PBS
          Storage
          Store at -20°C.

          * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

      • Applications
        • Application Description
          This antibody can be used for ELISA assay. Human CD8 is expressed either as an aß heterodimer or an aa homodimer by the cytotoxic/suppressor subset of T-cells and weakly by NK cells. CD8 acts as co-receptor in class I MHC-restricted antigen-induced T cell activation (binds to class I MHC molecules). It also participates in the thymocyte development.
      • Reference
        • Ellmeier, W. el. al. (1999) Annu, Rev. Immunol. 17, 523 - 554.
          Littman, D.R. et. al. (1985) Cell 40, 237 - 246.
          Perussia, B. et. al. (1983) J. Immunol. 131, 223 - 231.

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