Name: Anti-Human SV-40 antibody
Price: 1841.00 USD

Overview
- SV40, Simian Virus 40 is a polyomavirus that is found in both monkeys and humans. Like otherpolyomaviruses, SV40 is a DNA virus that has the potential to cause tumors. SV40 is believed tosuppress the transcriptional properties of tumor-suppressing p53 in humans through the SV40 largeT-antigen and SV40 small T-antigen. It is generally assumed that large T-antigen is the major proteininvolved in neoplastic processes and the large T-antigen predominantly exerts its effect throughderegulation of tumor suppressor p53, which is responsible for initiating regulated cell death(úapoptosisù), or cell cycle arrest when a cell is damaged. A mutated p53 gene may contribute touncontrolled cellular proliferation, leading to a tumor.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG2a
  
  Reactivity
  
  human
  
  Clone
  
  MRQ-4
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  1 ml supernatant in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
  
  Storage
  
  Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  * For research use only

Applications

Application	Dilutions
IHC	1:50 – 1:200

Anti-Human SV-40 antibody