Anti- human Sirtuin type 1 (SIRT 1) IgG fraction (monoclonal)

Anti- human Sirtuin type 1 (SIRT 1) IgG fraction (monoclonal)

Catalog Number:
A001277743AUS
Mfr. No.:
AUST_TM-501-55
Price:
$760
  • Size:
    150µg
    Quantity:
    Add to Cart:
      • Overview
        • IgG fraction from mouse monoclonal antibody (clone 3H2/G8) obtained by immunization using an ovalbumin-conjugated synthetic peptide corresponding to aa551–aa599 of human silent information regulator 2 homolog (Sirt1) protein. The IgG fraction was purified using Protein G-Sepharose.

          Please contact us at for specific academic pricing.

      • Properties
        • Antibody Type
          monoclonal
          Isotype
          IgG1
          Formulation
          Solution at 1.0 mg/mL in PBS (pH 7.2).
          Storage
          Store at -20°C.

          * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

      • Applications
        • Application Description
          This antibody can be used for ELISA assay (1: 8,000 dilution), immunoblot and immunoprecipitation analysis. It recognizes Sirt1 (120kDa), a NAD-dependent p53 deacetylase; protein involved in diverse processes ranging from regulation of gene silencing to DNA damage response in mammalian cells.
      • Reference
        • Langley, E. et al. (2002) EMBO J. 21, 2383 - 2396.
          Vaziri, H. et al. (2001) Cell 107, 149 - 159.
          Frye, R. (1999) Biochem. Biophys. Res. Commun. 260, 273 - 279.

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