Anti-human Lymphocyte Function Associated Antigen 3 (LFA-3); CD58 IgG fraction (monoclonal)

Anti-human Lymphocyte Function Associated Antigen 3 (LFA-3); CD58 IgG fraction (monoclonal)

Catalog Number:
A001277437AUS
Mfr. No.:
AUST_MA-CD58-6
Price:
$520
  • Size:
    200µg
    Quantity:
    Add to Cart:
      • Overview
        • IgG fraction from mouse monoclonal antibody (clone 2B2/D3) obtained by immunization of mice with human T lymphocytes. The IgG fraction was purified using Protein G-Sepharose.

          Please contact us at for specific academic pricing.

      • Properties
        • Antibody Type
          monoclonal
          Isotype
          IgG1
          Formulation
          Solution at 1.0 mg/mL in PBS
          Storage
          Store at -20°C.

          * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

      • Applications
        • Application Description
          This antibody can be used in immunoprecipitation, and flow cytometry, it also inhibits the cytolytic T lymphocyte (CTL) activity. It recognizes CD58 (also known as LFA-3), a 60-70 kDa membrane glycoprotein member of the immunoglobulin super family. CD58 is expressed on haemopoetic cells and it functions as an adhesion molecule mediating a co-stimulatory signal through CD2.
      • Reference
        • van der Merwe, P.A. & Davis, S.J. (2003) Annu. Rev. Immunol. 21, 659 - 684
          Wang, J-H. et. al. (1999) Cell 97, 791 - 803
          Wallner, B.P. et. al. (1987) J. Exp. Med. 166, 923 - 93

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