Anti-human CD45 (Leukocyte Common Antigen) IgG fraction (monoclonal)

Anti-human CD45 (Leukocyte Common Antigen) IgG fraction (monoclonal)

Catalog Number:
A001277436AUS
Mfr. No.:
AUST_MA-CD45-6
Price:
$520
  • Size:
    200µg
    Quantity:
    Add to Cart:
      • Overview
        • IgG fraction from mouse monoclonal antibody (clone 8G3/A1) obtained by immunization of mice with human lymphocytes. The IgG fraction was purified using Protein G-Sepharose.

          Please contact us at for specific academic pricing.

      • Properties
        • Antibody Type
          monoclonal
          Isotype
          IgG2a
          Formulation
          Solution at 1.0 mg/mL in PBS
          Storage
          Store at -20°C.

          * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

      • Applications
        • Application Description
          This antibody can be used in flow cytometry studies. It recognizes all isoforms of the CD45 (LCA). CD45 is a transmembrane tyrosine phosphatase, expressed on nucleated hematopoitic cells, which can exist in at least nine different isoforms resulting from tissue-specific alternative RNA splicing. CD45 functions as a leukocyte membrane receptor signal transduction. It plays an essential role in the regulation of leukocyte activation, development, and function.
      • Reference
        • Mustelin, T. et al. (2004) Mol. Immunol. 41, 687 - 700
          Trowbridge, I.S. et. al. (1994) Annu. Rev. Immunol. 12, 85 - 116
          Justement, L.B. et. al. (1991) Science 252, 1839 - 184

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