Anti-HSD3B2 antibody

Catalog Number:

A001035368STJ

Mfr. No.:

STJ26181

Price:

$297

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Overview
- The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-287 of human HSD3B2 (NP_000189. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 2; 3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type II; 3-Beta-Hsd II; 3-Beta-Hsd Adrenal And Gonadal Type Includes-3-Beta-Hydroxy-Delta(5-Steroid Dehydrogenase; 3-Beta-Hydroxy-5-Ene Steroid Dehydrogenase; Progesterone Reductase-Steroid Delta-Isomerase; Delta-5-3-Ketosteroid Isomerase (Gene ID:3284; UniProt:P26439)
  
  * For research use only

Applications

Application

WB; IF

Application	Dilutions
WB	1:500-1:2000
IF	1:10-1:100

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