-
-
Overview
-
This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de-and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.
Please contact us at for specific academic pricing.
-
- Properties
- Applications
-
Overview
Immunohistochemistry of paraffin-embedded human gastric using HRAS antibody (STJ110210) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human gastric cancer using HRAS antibody (STJ110210) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using HRAS antibody (STJ110210) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 20s.
Anti-HRas antibody
Anti-HRas antibody
Catalog Number:
A001017060STJ
Mfr. No.:
STJ110210
Price:
$297
Size:
Quantity:
Add to Cart:
.