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Overview
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The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene.
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- Properties
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Overview
Immunofluorescence analysis of U2OS cells using HPD antibody (STJ28588). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded rat kidney using HPD antibody (STJ28588) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse kidney using HPD antibody (STJ28588) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using HPD antibody (STJ28588) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 10s.
Anti-HPD antibody
Anti-HPD antibody
Catalog Number:
A001036673STJ
Mfr. No.:
STJ28588
Price:
$297
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