Anti-HMGCL antibody

Catalog Number:

A001017192STJ

Mfr. No.:

STJ110355

Price:

$297

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Overview
- The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human HMGCL (NP_000182. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Hydroxymethylglutaryl-Coa Lyase-Mitochondrial; Hl; Hmg-Coa Lyase; 3-Hydroxy-3-Methylglutarate-Coa Lyase (Gene ID:3155; UniProt:P35914)
  
  * For research use only