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Overview
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Recognizes common epitope on human HLA-DR, which is dependent on the association ofthe alpha and beta chains. Recognized epitope is conserved after fixation with glutaraldehyde andformaldehyde.HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides andpresent them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchoredin the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in theimmune system.Immunogen: Raji Burkitt's lymphoma cell line
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