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Overview
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This gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin-dependent kinase P-TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing results in multiple transcript variants.
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- Properties
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Overview
Western blot analysis of extracts of various cell lines, using HEXIM2 antibody (STJ117760) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 90.
Anti-HEXIM2 antibody
Anti-HEXIM2 antibody
Catalog Number:
A001024603STJ
Mfr. No.:
STJ117760
Price:
$297
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