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Overview
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This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.
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Overview
Immunohistochemistry of paraffin-embedded human liver cancer using HAO1 antibody (STJ28553) at dilution of 1:200 (40x lens).
Western blot analysis of extracts of various cell lines, using HAO1 antibody (STJ28553) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-HAO1 antibody
Anti-HAO1 antibody
Catalog Number:
A001036646STJ
Mfr. No.:
STJ28553
Price:
$297
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